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Biomechanical and user comfort data for the journal paper Using Biomechanical Signals and Gaussian Process Regression to Model Ankle Exoskeleton User Comfort. The data includes ground reaction forces, kinematic data (both marker positions and joint angles and velocity), kinetic data (joint moments and powers), metabolic cost, and comfort data for 13 subjects walking with a bilateral pair of ankle exoskeletons. 

The manuscript considers multivariate functional data analysis with a known graphical model among the functional variables representing their conditional relationships (e.g., brain region-level fMRI data with a prespecified connectivity graph among brain regions). Functional Gaussian graphical models (GGM) used for analyzing multivariate functional data customarily estimate an unknown graphical model, and cannot preserve knowledge of a given graph. We propose a method for multivariate functional analysis that exactly conforms to a given inter-variable graph. We first show the equivalence between partially separable functional GGM and graphical Gaussian processes (GP), proposed recently for constructing optimal multivariate covariance functions that retain a given graphical model. The theoretical connection helps to design a new algorithm that leverages Dempster’s covariance selection for obtaining the maximum likelihood estimate of the covariance function for multivariate functional data under graphical constraints. We also show that the finite term truncation of functional GGM basis expansion used in practice is equivalent to a low-rank graphical GP, which is known to oversmooth marginal distributions. To remedy this, we extend our algorithm to better preserve marginal distributions while respecting the graph and retaining computational scalability. The benefits of the proposed algorithms are illustrated using empirical experiments and a neuroimaging application. 

Abstract This case study analyzes the 17 May 2019 cyclic, tornadic supercell from southwest Nebraska observed by the Targeted Observation by Radars and UAS of Supercells (TORUS) field experiment. Specifically, 12 multi-Doppler wind syntheses are generated over a 96-min period from 2301 UTC 17 May to 0037 UTC 18 May using two P-3 airborne radars and the ground-based NOXP research radar. Synthesized winds and reflectivity are assimilated into a diabatic Lagrangian analysis for the retrieval of thermodynamic data. The 4D wind fields are found to correlate well with observed tornadic and nontornadic periods, and several storm-scale features related to low-level mesocyclone (LLM) and near-ground rotation processes are documented. This includes vortex line arches that are a defining feature during the first EF2 tornado, followed by an occlusion process and reorganization period. During the most active tornadic period, backward trajectories reveal both inflow parcels and forward-flank parcels participate in the core of the 0–1-km rotation. While tilting of streamwise vorticity into vertical vorticity and subsequent powerful vertical stretching occurs for both inflow and forward-flank parcels, the solenoidal generation of streamwise vorticity is dominant with the latter. This resembles streamwise vorticity currents found within numerical simulations. Last, an intense left-flank convergence boundary develops coincident with the intensification of storm-relative inflow winds, with its formation and dissipation correlated with the final tornado. The 96-min analysis period with 4D kinematic and thermodynamic data makes this study one of the most detailed supercell case studies presented in the literature. Significance StatementA detailed analysis of a supercell that produced nine tornadoes within a 96-min period is presented. The supercell was observed by five radars, which are used to obtain information about the 3D wind, temperature, and moisture fields. Although computer simulations can provide detailed looks into supercell processes, collecting and analyzing observed supercell data of this quality is challenging and rare. We identify features within the supercell that are correlated with periods of strong and weak tornado production. Additionally, we identify the source region of air that is associated with low-level rotation in the supercell and comment on the importance of temperature gradients observed within the supercell, comparing these results to what has been found in simulations. 

Abstract This paper is the first in a forthcoming series of works where the authors study the global asymptotic behavior of the radial solutions of the 2D periodic Toda equation of typeA_n. The principal issue is the connection formulae between the asymptotic parameters describing the behavior of the general solution at zero and infinity. To reach this goal we are using a fusion of the Iwasawa factorization in the loop group theory and the Riemann-Hilbert nonlinear steepest descent method of Deift and Zhou which is applicable to 2D Toda in view of its Lax integrability. A principal technical challenge is the extension of the nonlinear steepest descent analysis to Riemann-Hilbert problems of matrix rank greater than 2. In this paper, we meet this challenge for the casen = 2 (the rank 3 case) and it already captures the principal features of the generalncase. 

As major adhesion receptors, integrins transmit biochemical and mechanical signals across the plasma membrane. These functions are regulated by transitions between bent and extended conformations and modulated by force. To understand how force on integrins mediates cellular mechanosensing, we compared two highly homologous integrins, αIIbβ3 and αVβ3. These integrins, expressed in circulating platelets vs. solid tissues, respectively, share the β3 subunit, bind similar ligands and have similar bent and extended conformations. Here, we report that in cells expressing equivalent levels of each integrin, αIIbβ3 mediates spreading on softer substrates than αVβ3. These effects correlate with differences in structural dynamics of the two integrins under force. All-atom simulations show that αIIbβ3 is more flexible than αVβ3 due to correlated residue motions within the α subunit domains. Single molecule measurements confirm that αIIbβ3 extends faster than αVβ3. These results reveal a fundamental relationship between protein function and structural dynamics in cell mechanosensing. 

Polyploidy and subsequent post-polyploid diploidization (PPD) are key drivers of plant genome evolution, yet their contributions to evolutionary success remain debated. Here, we analyze the Malvaceae family as an exemplary system for elucidating the evolutionary role of polyploidy and PPD in angiosperms, leveraging 11 high-quality chromosome-scale genomes from all nine subfamilies, including newly sequenced, near telomere-to-telomere assemblies from four of these subfamilies. Our findings reveal a complex reticulate paleoallopolyploidy history early in the diversification of the Malvadendrina clade, characterized by multiple rounds of species radiation punctuated by ancient allotetraploidization (Mal-β) and allodecaploidization (Mal-α) events around the Cretaceous–Paleogene (K–Pg) boundary. We further reconstruct the evolutionary dynamics of PPD and find a strong correlation between dysploidy rate and taxonomic richness of the paleopolyploid subfamilies (R^2 ≥ 0.90, P < 1e-4), supporting the “polyploidy for survival and PPD for success” hypothesis. Overall, our study provides a comprehensive reconstruction of the evolutionary history of the Malvaceae and underscores the crucial role of polyploidy–dysploidy waves in shaping plant biodiversity. 

Abstract We present spatially resolved measurements of SO₂and NaCl winds on Io at several unique points in its orbit: before and after eclipse and at maximum eastern and western elongation. The derived wind fields represent a unique case of meteorology in a rarified, volcanic atmosphere. Through the use of Doppler shift measurements in emission spectra obtained with the Atacama Large Millimeter/submillimeter Array between ~346 and 430 GHz (~0.70–0.87 mm), line-of-sight winds up to ~−100 m s⁻¹in the approaching direction and >250 m s⁻¹in the receding direction were derived for SO₂at altitudes of ~10–50 km, while NaCl winds consistently reached ~∣150–200∣ m s⁻¹in localized regions up to ~30 km above the surface. The wind distributions measured at maximum east and west Jovian elongations and on the sub-Jovian hemisphere pre- and posteclipse were found to be significantly different and complex, corroborating the results of simulations that include surface temperature and frost distribution, volcanic activity, and interactions with the Jovian magnetosphere. Further, the wind speeds of SO₂and NaCl are often inconsistent in direction and magnitude, indicating that the processes that drive the winds for the two molecular species are different and potentially uncoupled; while the SO₂wind field can be explained through a combination of sublimation-driven winds, plasma torus interactions, and plume activity, the NaCl winds appear to be primarily driven by the plasma torus. 

In the introduced range, the successful establishment of an invasive species may be influenced by positive plant-plant interactions. Pre-existing vegetation, particularly conspecific mature trees, can shape the availability and attributes of microsites, thus potentially creating favorable conditions for the establishment of conspecific seedlings through facilitation. Pines are widely introduced in the Southern Hemisphere primarily as forestry plantations; these pines can become invasive, causing detrimental effects on local ecosystems and economies. In the high-elevation grasslands of the Sierras de Córdoba, Central Argentina, pines have begun to invade the native grassland as a result of improper (or lack of) management of pine plantations. During early pine invasion in this semi-arid grassland, we aimed to quantify the influence of adult live pines and on congeneric pine seedling recruitment and survival. For this, 48,000 seeds of Pinus elliottii and P. taeda were sown in three consecutive field trials, under different tree status treatments: live pines, dead pines, and no pines (i.e., open grassland). Seed were sown with and without irrigation and seeded microsites were oriented to the north and south of the live and dead trees. We also considered the hillslope aspect where the sites were located. Our results show that pine seedling recruitment was 57 % higher under live pines compared to dead pines and no pines treatment, but only in the trials that were not irrigated. Microsites south of the live pine trees, more shaded from direct sunlight in the Southern hemisphere, presented 36 % more pine seed germination than those to the north. In terms of topography, hillslope aspects with lower solar incidence (wetter hillslopes) also showed higher pine seedling recruitment. Our results suggest that moisture availability is a dominant factor driving further invasion, and that adult pines may be facilitating the invasion process by creating moister microsites for germination and pine seedling establishment. Thus, the early removal of adult pines is important to consider in the management of pine invasions. They do not only serve as a source of propagules, but also positively affect the establishment of their congeneric seedlings.